Comparison between the Effect of using Similar Wedges and Opposed Wedges in Brain Tumor Cases

Document Type : Original Article

Authors

1 Radiation Therapy Depart. , Armed Forces Hospital, Alexandria.

2 Oncology Depart. , Faculty of Medicine, Alexandria University.

3 Medical Biophysics Depart. , Medical Research Institute, Alexandria University.

4 Radiation Therapy Depart. , Ayaddi Al Mustakbal Hospital, Alexandria.

5 Physics Depart. , Faculty of Science, Damanhour University.

Abstract

Abstract
Introduction: Radiotherapy still the most facilitated modality for treatment malignant brain tumors with or without chemotherapy and after surgery or when surgery is impossible. Purpose: Comparison between the effects of three planning techniques with similar, opposed and non-wedges in brain tumor cases. Methods: Twenty patients with brain tumors (Glioblastoma Multiform) of both sexes were enrolled in the study. A LINAC with 6MV photon beam was used to deliver the prescribed dose. The whole brain technique was applied to each patient and the planning was constructed with non-wedges, similar wedges and opposed wedges within 95% to 107% of the prescribed dose as recommended by the RTOG. The considered organs at risk were; Right and Left (eyes, lenses, and optic nerves), optic chiasma and the brain- stem. Results: The results showed significant difference (at the level P<0.05), between the three planning based on the conformity, homogeneity indexes, global max, and the doses received by the OARs. The results were discussed.

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